Welcome to the Ulijn Group website. Our lab is focused on the use of simple versions of the molecular building blocks of life to produce materials and systems with controllable structural, photonic, electronic, and biological properties. These properties open up wide-ranging applications in energy, biomedicine, environmental protection, food, cosmetics, and personal care. [Group Members and Full Biography]
We Are Recruiting!
@asrc_gc is seeking to recruit two highly motivated postdoctoral scholars to research systems-based design of biomolecular modalities and materials. Researchers who have experience or interests that bridge computation/theory and experiment are especially encouraged to consider these positions.
Come and join us in NYC! Apply here.
In Situ, Noncovalent Labeling and Stimulated Emission Depletion-Based Super-Resolution Imaging of Supramolecular Peptide Nanostructures
This paper by Mohit, with contributions from Jiye, Richard and Deborah demonstrates a new and remarkably simple method to fluorescently label peptide nanostructures for their visualization in solution with super-resolution microscopy. We show that by simply mixing a small amount (0.1 mole%) of a commercially available dye (Alexa-488) with cationic self-assembling peptides gives rise to selective electrostatic association of the dyes with the peptide nanostructure surface, which enables imaging using Stimulated Emission Depletion (STED) super-resolution microscopy. The method gave new insights into the hierarchical organization of peptide nanostructures, and enabled visualization of enzymatic degradation of peptide nanofibers which could be imaged in real-time in situ.